As far as widespread full stack goes, it depends on what the aim of the code is. If you're collaborating, then no, as the program can be unreadable and leaving comments as insurance is too timeconsuming. In the end, we usually try to find a reasonable balance between using concise syntax and structure while the code is still easily readable to a third party. But when in comes to more specialized areas I don't have the experience to say so I guess it's possible.